KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCY10
All Species:
6.36
Human Site:
T615
Identified Species:
23.33
UniProt:
Q96PN6
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96PN6
NP_060887.2
1610
187135
T615
R
E
I
S
R
M
S
T
L
K
K
Q
K
Q
L
Chimpanzee
Pan troglodytes
XP_524953
1610
187002
K615
R
E
I
S
R
M
S
K
L
K
K
Q
K
Q
L
Rhesus Macaque
Macaca mulatta
XP_001114224
1262
144000
I411
N
I
S
N
P
G
K
I
Y
E
Y
L
G
H
R
Dog
Lupus familis
XP_537210
1610
186431
T615
R
E
V
S
K
M
T
T
L
R
K
Q
K
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0T9
1614
186389
K616
R
E
M
S
R
M
S
K
I
R
K
Q
K
Q
L
Rat
Rattus norvegicus
Q9Z286
1608
185835
K616
R
E
M
S
R
M
S
K
I
R
K
Q
K
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001020380
1868
209735
S721
P
R
C
L
H
M
T
S
E
H
Q
T
K
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
28.7
80.4
N.A.
76.3
77.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
26.1
Protein Similarity:
100
99.4
45.6
89.7
N.A.
86.8
87.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
45.7
P-Site Identity:
100
93.3
0
73.3
N.A.
73.3
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
93.3
13.3
100
N.A.
93.3
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% A
% Cys:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
72
0
0
0
0
0
0
15
15
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
15
0
0
0
0
0
0
15
0
0
% G
% His:
0
0
0
0
15
0
0
0
0
15
0
0
0
15
0
% H
% Ile:
0
15
29
0
0
0
0
15
29
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
15
0
15
43
0
29
72
0
86
0
0
% K
% Leu:
0
0
0
15
0
0
0
0
43
0
0
15
0
0
86
% L
% Met:
0
0
29
0
0
86
0
0
0
0
0
0
0
0
0
% M
% Asn:
15
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
15
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
15
72
0
72
0
% Q
% Arg:
72
15
0
0
58
0
0
0
0
43
0
0
0
0
15
% R
% Ser:
0
0
15
72
0
0
58
15
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
29
29
0
0
0
15
0
0
0
% T
% Val:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
15
0
15
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _